1. parisbouckle@gmail.com' suzanne watson
    August 14, 2015 @ 10:47 am

    what dosage would you recommend for a healthy 64 yo female?

  2. Serrapeptase: an Enzyme That Treats Inflammation, Arthritis, Scar Tissue and More | alternative medicine or natural cures
    August 15, 2015 @ 5:05 pm

    […] See: Serrapeptase: Carotid Artery Blockage […]

  3. abid818@yahoo.com' abid
    August 28, 2015 @ 9:05 pm

    IS Serrapeptase to be an extraordinary substance for blocked heart stunts. if yes then how much time it takes for treatment of three blocked heart stunts and how we start this treatment beyond from usa. if any refers of doctors or medicine in pakistan .

  4. abid818@yahoo.com' abid
    August 28, 2015 @ 9:23 pm

    how open three blocked heart stents , how we start its remedy or treatment .

  5. Dr. Michelle Kmiec
    September 14, 2015 @ 6:40 am

    Hello, simply follow the dosage recommendation stated in the article!

  6. Fineirons@gmail.com' Mike Kellerman
    October 26, 2015 @ 3:04 pm

    Hello Dr Michelle Mkiec.
    I too was wondering how much serrapeptase I should be taking to clear blocked carotid bulb and distal common artery please any info will help .i started last night with 700,000 SU’s

  7. Dr. Michelle Kmiec
    October 27, 2015 @ 4:08 pm

    Hello, did you mean IU’s? I do not believe you need to take 700,000 IU’s if this indeed is what you meant to say. Please refer to the recommended dosages.

  8. coolgsd@yahoo.com' H. Teel
    February 26, 2016 @ 5:38 pm

    Dr. You really don’t know much about this enzyme do you?

  9. chazz1051@gmail.com' Chazz
    March 2, 2016 @ 8:07 pm

    Hello Dr. Kmiec

    If serrapeptase is used for clearing carotid arteries, what or how does the waste material keep from blocking other arteries? Is the plaque liquified or what?
    Thank you,


  10. Dr. Michelle Kmiec
    March 5, 2016 @ 8:11 am

    Hello H. Teel! Thanks for your question. Yes, I do know quite a bit about this enzyme including the research that supports it.

  11. jkslent@live.com' Jake
    March 15, 2016 @ 12:17 pm

    “Hello H. Teel! Thanks for your question. Yes, I do know quite a bit about this enzyme including the research that supports it. ”

    Then why didn’t you know what SU’s are? SU’s are Serrapeptase Units. I suspect, that’s why you were asked that question by H. Teel. The recommended dosage would be 240,000 SU’s per day. Which most can safely increase to higher dosages of 700,00SU’s to clear major blockages, but don’t stay on that higher dosage for extended periods of time. Also, stop taking Serrapeptase approximately 2 weeks prior to any scheduled surgeries, as it can prevent blood from clotting.

  12. Dr. Michelle Kmiec
    March 15, 2016 @ 1:35 pm

    Yes I did know about serratiopeptidase activity units (SPU) or serratiopeptidase units (SU) – not “serrapeptase” units. Thanks for asking. 🙂 However this is not the unit on all brands and that is the problem and confusion for many people. On some serrapeptase brands you will find international units (IU), and still on others you will find mg. Many people do not think there is a difference in these measurements when recommending a proper dosage and that could lead to not getting the desired results or causing an issue as you mentioned with “blood thinning”.

  13. pgibbs_43@msn.com' Peter
    March 18, 2016 @ 4:24 am

    Hallo Dr Kmiec, After a heart attack over a year ago I start taking serrapeptase, initially 120,000 and then increasing to 250,000 IU, for nearly a year now. I certainly feel better but don’t know if it’s the serrapeptase or my changed lifestyle, improved diet more exercise or even the standard medication from our beloved NHS. I also don’t know about the effect it’s had on my atherosclerosis, it’s certainly done me no harm and I plan to continue taking it for the foreseeable future.
    Given it’s reputation as a wonder cure for cardiovascular health I find it very surprising that more that more scientific research has not been done to support what is until now a great deal of anecdotal evidence. I’d like to know for certain if it’s really dissolving my arterial plaque, how would I know my ? Is there research of which I am unaware ? and if so please point me in the right direction. Incidentally, my wife is taking it at the same dosage and swears that it reduced her blood pressure, eased her arthritis, and improved lung capacity. However she could be giving it credit which is not due, as she has been losing weight and exercising more.

  14. johnramuseth@gmail.com' GJ Borseth-Rasmussen
    March 27, 2016 @ 10:31 am

    we would like to know the extra ingredient in serrapeptase for choked arteries especially in the neck. Where can I order it.

  15. candidajoel@yahoo.com' Joel
    March 29, 2016 @ 7:31 am

    I feel a pressure in my chest at times. I had three blockages five years ago which were cleared with chelation. I now feel a light pressure in my chest and the doctor is again treating me with chelation. Can I start a treatment with serrapeptase. Please let me the dosage in mg. and the number of capsules per day and for what duration of time I should be taking serrapeptase. Also let me know if any manufacturer in India is making serrapeptase capsules.

  16. rromans1013@gmail.com' Milton Thorpe
    April 30, 2016 @ 10:30 pm

    Hi,Almost a year ago, I had a mini stroke. Had some test done and found some blockage in the corodid arty (51 to 69 percent) Am currently taking 80,000 spu 3 or 4 times per week. Have been on this dosage for about 10 months now. Do you think that I am taking the right amount or shud I increase the dosage? Feel OK and will go back to family dr. for check up in a couple of months. By the way I turned 81 last jan 20. Thanks for your time…..Milt

  17. Gedred46@googlemail.com' Ged
    May 25, 2016 @ 2:22 am

    Hi doctor, i have recently had angioplasty.ive had one stent fitted in artery near my heart. Im taking beta bisoprolol, perindoprol, statins and asprin. Can take serapeptase alongside this medication? Thanks Ged.

  18. susielynnprice@gmail.com' Susie Price
    June 16, 2016 @ 4:51 pm

    I would like to know if serrapeptaste will help clear an illiac artery..if so what about dosage

    Thanking you in advance.Susie

  19. normell60@hotmail.com' Michael Elliott
    June 20, 2016 @ 7:43 am

    Hi Doctor, I’ve read, with greaat interest the vstious questions posed by users of serrapeptase, but sadly you have not ansered some major queries i.e. if plaque is disolved, will the debris block smaller blood vessels? I have a blocked right carotid artery and partially blocked left, so am very keen to check out all possible remedies. I am currentlt taking 2 x 260000 su’s of serrapeptase (at around 3 – 4 a.m. to ensure an empty stomach )! I hope to see your comments in due course.

  20. caseyclRk48@gmail.com' Kathleen Clark
    July 1, 2016 @ 12:58 pm

    Help! I’m desperate and out of time! I am a 67 yo female with blocked carotid arteries. 60% blockage on left side and 80% blockage on right side. I am also a singer and fear surgery of any kind. PLEEEEEESE answer me quickly. Unfortunately I live on an indigent budget as a retired social worker and missionary. Please advise.

  21. martineh16@hotmail.com' Martine
    August 2, 2016 @ 11:10 am

    I have just read this artical and it is quite interesting. My father has vascular dementia caused by several CVA’s. He is using asperines now and has statines called Simvastine for his cholesterol. Do you think that using this enzym is usefull for him?Should he stop with the statines or should he use both?

  22. Maurice.daher@gmail.com' Maurice
    September 21, 2016 @ 11:33 pm

    Have anyone checked there CT heart scan calcium score. To find out whether has been any reduction of the calcium deposit in the arteries… Currently I have two blockage of 40 and 60 percent and will be trying this new therapy… Also started taking vitamin k2 with 10,000iu of vitamin d, to remove any calcium and put it where it belongs…

  23. Nevada_Smith@live.com' Nevada Smith
    September 22, 2016 @ 2:40 am

    A couple weeks ago I had an episode of Amaurosis fugax involving my left eye. It didn’t last long. Here’s the thing: I have been taking serrapeptase for some time. I would say at least 18 months. In the beginning I began taking it for superficial clots in my right leg that were causing me significant pain and discomfort. My initial dosage was 120,000 SUs three times a day. I later reduced that to 120,000 SUs twice a day. Because I was already taking serrapeptase when I had Amaurosis fugax, I was concerned with whether or not there was a possibility that the serrapeptase caused the Amaurosis fugax and what I should do. My father died with a stroke and my paternal grandmother also had a stroke. I have no other risk factors. I plan on starting an exercise routine today as I just recently retired and have no excuse not to. I also read that mercury toxicity is linked to causing blood clots. I had my dental amalgams replaced last January and have been following the Andy Cutler Chelation protocol since then currently taking 200 mg of alpha lipoic acid every three hours for 72 hours a week. Could the ALA and serrapeptase together be overdoing it or should I continue my regimen?

  24. sternresearch@gmail.com' star
    November 1, 2016 @ 10:44 pm

    serrapeptase does it better then nattokinase ?

  25. barbbat@yahoo.com' BarbB
    November 11, 2016 @ 6:37 pm

    The doctor doesn’t seem to be answering questions anymore.

  26. Dr. Michelle Kmiec
    November 13, 2016 @ 10:12 am

    Hello Barb, Besides comments/questions on this website I also receive many emails in reference to different health conditions as well as questions related to blog posts such as this one. I do try to answer as many questions as I can within my schedule, though sadly I can’t always get to them all.

  27. ko75033@gmail.com' Kyle
    November 17, 2016 @ 7:36 pm

    Hello, Does somebody have heard about serrapeptase helping with atrial fibrillation. Is that could be dose dependent or in combination with any other natural supplement. Thank You!

  28. Danny1985wales@gmail.com' Daniel
    December 7, 2016 @ 3:33 pm

    Hello there PETER good to meet you i’m Daniel, i seen your comment about you having a Heart attack, i have 2 Uncles unfortunately pass away from Heart attacks, and i need to be safe about mine i am only 30 years old but really runs in the family, i am starting Serrapeptase too, and wanted to know Peter what Brand you stayed with for majority of your Serrapeptase cycles, and which is best supplier, i definitely going to Buy it, just like to make sure as this a different kind of Enzyme. thanks & kind regards

  29. Scottysegal@yahoo.com' Scott Smith
    January 4, 2017 @ 7:31 am

    If someone has a link to clinical research please post it here. Also, if you have a before and after calcium score, please post it. I’ve not yet tried serrapeptase because I’ve not yet seen a trusted study. I take a lot of supplements so it would be hard for me to personally prove out the effectiveness of this. I take a supplement called NancobacTX that is supposed to remove plaque. It’s not cheap. My cardiologist recommended it because I have a calcium score of 153 as a 46 year old. He knows of no other proven method and he’s a naturopath MD so he’s very open minded. I’m going to forward this to him for his opinion. I just started taking the supplement mentioned above about 2 months ago, so I don’t have any ‘after’ evidence yet. Also, you really shouldn’t get a calcium score more frequently than every 18 months to 2 years due to radiation. If you live in Texas, you can get calcium score test for free. I don’t live there and without insurance it costs $125. Pretty low for an uninsured medical test. I’d love to be able to do a faster re-check of my data. Please post your before and after data from serrapeptase if you have it.

  30. clark.toddanddebbie@gmail.com' Debbie Clark
    February 10, 2017 @ 9:47 pm

    You referred to an article that tells the dosages of Serrapeptase for different diseases. Where is this article? I could not find it. I need to know how much you would recommend for heart plaque. We are not sure what percentage is in the LAD artery, but could be greater than 70%.

    Thank you

  31. Dovstein3@gmail.com' Dov
    February 11, 2017 @ 8:43 pm

    I find it hard to trust what you write because your use of language and grammar is very approximate, careless and inaccurate. examples: ‘Serrapeptase dissolves ‘dead’ tissue like or e.g. not both silk…’ and ‘we see patients where surgeons were reluctant to operate or to apply drill or laser technology such occluded carotids.’ and ‘…an extraordinary substance for safety( safely) removing fibrous blockages from coronary arteries, particularly the carotid arteries (these are not coronary arteries) found in the neck, which supply blood ( to the) brain. I expect more precision from someone purporting to give accurate information about something as important as this powerful medication. Dr Stein, MB

  32. Online Holistic Health
    February 12, 2017 @ 2:15 pm

    Hello Dr. Stein, MB

    Thank you for you comment however, I am not the author of this article. Please refer to the beginning of the article where it clearly states who the author is: “Silk Worm Enzymes for Carotid Artery Blockage
    “The Therapeutic Results are Excellent, Certainly Lifesaving” By Dr. H A Nieper (FYI: 1928 – 1998). I am sorry, but I do not feel it appropriate to edit his work as I it would be disrespectful on many level. Moreover, I disagree with you interpretation of, “safety removing fibrous blockages from coronary arteries, particularly the carotid arteries found in the neck, which supply blood brain. I believe it is clear that Dr. Nieper was referring to two separate areas of the body: The arteries of heart and of the neck.

    If you like, please feel free to read an article that I did write… Serrapeptase: An Enzyme You Should Not Be Without!

    I hope this clears up your confusion!

    Wishing you optimal health, Dr. Michelle Kmiec, DC

  33. Online Holistic Health
    February 12, 2017 @ 2:19 pm

    Hello Debbie, To learn more about serrapeptase, please refer to Serrapeptase: An Enzyme You Should Not Be Without! . And for even more information, please click HERE.

    I hope that helps!

  34. sledgehammer58@hotmail.com' Kelli
    February 13, 2017 @ 8:48 pm

    I am trying to find out if there is a difference between serrapeptase and serrazimes so I know what to order. I can only find out that serrazime is a brand and that it acts like serrapeptidiose. Help???

  35. Danny1985wales@gmail.com' Daniel
    May 7, 2017 @ 7:29 am

    Hello there Dr. Michelle Kmiec, i would like to ask a important question as to your Extensive Research on Serrapeptase, if someone taking Serrapeptase as myself suffers Chest pains is that a sign of something working or a bad sign? and if this Enzyme does clear old tissue which it does, or Plaque arterial, does that me i have some near my Heart area and that’s how i got chest pains, if you can give me a Article about people getting Chest pain with Serrapeptase and why. or explain if i should continue taking it if i am getting Chest pain all the time with it. Kind regards, God Bless

  36. jasonkaramo@yahoo.com' Jason Keita Karamo
    May 30, 2017 @ 11:48 am

    Dr. Id like to know if its is safe to use serrapeptase 40,000 I.U.’s 3 x a day for kidney disease and COPD? I also wonder if the blockages in the lungs and kidney arteries will have difficulty being passed out of the body if there is Kidney disease sense the kidneys obviously filter waste out of the body.

  37. joanncarter2128@gmail.com' JoAnn Holloway
    October 21, 2017 @ 9:08 am

    Do you have to buy the Serrapeptease with an Enteric Coating to be effective for the arteries?

  38. richard3@sonic.net' Richard Murphy
    March 7, 2018 @ 2:38 am

    Where can I read your answers to these questions?

  39. Online Holistic Health
    March 7, 2018 @ 7:58 am

    Hello Richard, I have answered many of the questions. All you have to do is start from the top and scroll down. Look for my name (Dr. Michelle Kmiec) or Online Holistic Health for responses. 🙂

    Also, many people have emailed me as well.

    Hope that helps!

  40. master7727@gmail.com' Edward
    May 24, 2018 @ 8:42 am

    Hi Dr. Is there any clinical research or double-blind studies on the effectiveness of serrapeptase? Thank you.

  41. dlwaegeman@yahoo.fr' Dominique
    June 13, 2018 @ 9:54 am


    I have three questions concerning the serrapeptase :

    1. I understand that the serrapeptase is supposed to “clean” the body ; therefore, it is a detox product ; Can the serrapeptase be taken by a person with an important renal failure ?

    2. In case of difficulty to swallow the capsule, is it possible to open it and put the powder in a compote or a yogurt ?

    3. Where can I buy the best serrapeptase ?

    Thank you in advance.


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