Vitamin B15 (Pangamic A)

Vitamin-B15Vitamin B15 (Pangamic Acid)

Just what is “Vitamin” B15 anyway? Indeed this is the question of the day!

It is easy to see how there can be confusion regarding Vitamin B15, or is it pangamic acid, or DMG, or calcium pangamate? First of all, my guess is that many of you have never heard of any of these terms.

This would not be the case, however, if you lived in Europe or Russia (where this vital nutrient was first discovered.) And some of you may actually remember this controversial substance from the 1970’s.

When researching Vitamin B15, there are many websites (both amateur blogs as well as professional websites) that incorrectly label Vitamin B15.

Some claim it to pangamic acid, others claim it to be calcium pangamate, while others claim it to be N, N dimethylglycine (DMG). And then there are many websites that call Vitamin B15 all three names, suggesting that they are synonymous with each other.

So let’s take a look at each so as to be clear as to what they really are. The following have been all said to be, Vitamin B15:

  1. Pangamic acid: Is an ester derived from gluconic acid and dimethylglycine
  2. Calcium pangamate: Is the calcium salt of pangamic acid
  3. N, N-Dimethylglycine (DMG): Is a derivative of the amino acid glycine

Anyone can look at these three obviously different compounds and see that could not be mistaken for the same thing. Yet, to confuse you even more, the understood meaning of Vitamin B15 differs depending on geographical location.

Meaning, that the USA infers that Vitamin B15 is pangamic acid, but Russia infers Vitamin B15 as calcium pangamate.

Now hold on!

Not the calcium pangamate that I have listed above, but the combination of the calcium salt of pangamic acid (calcium pangamate), calcium gluconate and N,N-dimethylglycine (DMG), which they called Calgam.

This is the Russians calcium pangamate or Vitamin B15.

Wow right!

Try to be patient, I know I’ve just thrown you into the deep end of chemistry terminology, but it will all come together as you keep reading…I promise.

Briefly, let’s discuss Calgam.  

In the 1960’s, Bukin and Garkina of the Russian Academy of Medical Sciences filed for a US Patent, which was granted in Sept. of 1975, for a process of manufacturing pangamic acid as a calcium salt. They called their product “calcium pangamate”.  However, as you just learned, this product was actually a mixture that included the calcium salt of pangamic acid, calcium gluconate and N, N-dimethylglycine (DMG).

Again, it was this mixture that was considered to be calcium pangamate (Vitamin B15). It was used for a variety of health conditions in Russia since 1962. Then, a few years later in 1967, their calcium pangamate product was exhibited at the Montreal Expo under the label of Calgam.

Here in the USA, the FDA currently recognizes so-called “Vitamin B15” as pangamic acid and they do not acknowledge it as a Vitamin. They banned its use as being an “unsafe food additive”. Since pangamic acid is an ester derived from gluconic acid and N, N-dimethylglycine (DMG), any products containing these compounds were also banned. In brief, esters are organic compounds that result from the interaction between acids or alcohol.

The FDA has also banned the Russians’ product, Calgam, despite all of their research and excellent health-related results (Of course!)

So why then would the FDA ban pangamic acid? And what do they mean by “unsafe food additive”? Well these are the second and third questions of the day!

The answers will surprise you! 

Find out the truth regarding Vitmain B15 by reading…Vitamin B15 is Unsafe: The FDA Contradiction.

I guarantee you’ll be shocked!


Why do you need Vitamin B15 (“Pangamic acid”)?

  • Intermediary metabolite involving several physiological systems
  • Improves in oxygen utilization
  • Improves circulation
  • Improves glucose metabolism
  • Aids in production of neurotransmitters
  • Aids in production of hormones
  • Aids DNA
  • Enhances the immune system by increasing the immune response
  • Normalizes blood glucose levels
  • Supports liver detoxification
  • Methylation of DNA
  • Antiviral
  • Antibacterial
  • Anti-tumor
  • Detoxifies chemical poisoning
  • Enhances liver function


Conditions Related to Vitamin B15 Deficiency

  • Cancer
  • Angina pectoris
  • Atherosclerosis
  • Chronic Inflammation
  • Arthritis
  • High LDL Cholesterol
  • Hypertension
  • Cirrhosis of liver
  • Asthma
  • Emphysema
  • Alcoholism
  • Autism
  • Hepatitis
  • Hypoxia (low oxygen levels in the body)
  • Rheumatic fever
  • Rheumatism
  • Chemical poisoning
  • Exposure to chronic environmental pollutants
  • Chronic pain
  • Chronic fatigue
  • Seizures



The following dosage refers to DMG:

Currently considered the leading expert in organic biochemistry, Dr. Roger V. Kendall has been a pioneer in DMG research and therapeutic applications. With over twenty-five years of experience he presently holds seven U.S. Patents, two European Patents, with six of them on DMG alone!

Interestingly, it’s the biochemists and chemists that have paved the way in revolutionary health research. Such is the case with Dr. Kendall and Dr. Linus Pauling (who did ground-breaking research regarding high-dose Vitamin C therapy.) Oddly, despite their contributions to human healthcare within their field of expertise that directly relates to the biochemical aspects of the human body, these doctors (and so many more) have been shunned by the modern medicine profit machine, which includes Big Pharma and insurance companies.

If you are interested in what an actual organic biochemist discovered in his long years of research, then I invite you to read on!

The following dosages have been shown to be important to human physiological metabolism.

Based on his research, 125 mg – 2500 mg per day in divided dosages is most commonly used. DMG, unlike some other nutritional supplements, DMG is not dependent upon taking with or without meals; although, between meals seem to be most advised. Because DMG breaks down in the body quickly, it is best to best to divide the doses through the day.



Research regarding the upper limit of DMG has proven to be extremely high. Doses as high as 6000 mg per day have been taken without any signs of toxicity making DMG is an extremely safe nutrient.




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