32 Comments

  1. diogenes0003@aol.com' Don Carroll
    Jan 14, 2012 @ 15:11:18

    Excellent report on lithium – orotate. I have just recently
    began taking the “orotate”. I did feel a very slight feeling
    in my head for a short time during the day. But not now. I now don’t notice it at all.

    I’m quite happy so far and grateful for this research.

    Is Honesty and sincerity beginning to make a comeback!

  2. caitlindhage@mailc.net' mujeres solteras
    May 02, 2014 @ 16:10:08

    Appreciate the recommendation. Will try it out.

  3. senn590@hotmail.com' Dave
    Jul 27, 2014 @ 13:35:40

    Except the premise (“possibility”) that lithium orotate has higher bioavailability appears not to be true: Lithium orotate, carbonate and chloride: pharmacokinetics, polyuria in rats.Br J Pharmacol. 1976 Apr;56(4):399-402. No differences in the uptake, distribution and excretion of the lithium ion were observed between lithium orotate, lithium carbonate and lithium chloride after single intraperitoneal, subcutaneous or intragastric injections (0.5-1.0 mEq lithium/kg) or after administration of the lithium salts for 20 days in the food.

    There is evidence that low-dose lithium can be beneficial irrespective of which salt, but low-dose lithium orotate is not remotely equivalent to high-dose lithium carbonate. Sales of lithium carbonate and chloride are banned, that’s why orotate and aspartate are sold as supplements.

  4. Dr. Michelle Kmiec
    Jul 28, 2014 @ 10:35:32

    Hi Dave!Thanks for your comment! However, I always like to look who is doing the research. In this case, Pharmacol isn’t exactly an unbiased party. With that said, all research is very useful in finding the truth. Ed Sharpe wrote an article for Global Healing Center that is quite good. I like that the article is supported by research, and that the research list is more extensive than one [potential study result. Here’s the link: http://www.globalhealingcenter.com/calcium-orotate/orotates-mineral-transporters

  5. maddypaints@gmail.com' Madeline Winter
    Oct 27, 2014 @ 20:16:04

    Hi, I am a 65 year-old female who has been detoxing from antidepressants and benzodiazepines for over a year. My brain was fried after 20 years of pharmaceuticals. I recently developed symptoms of no-Pilate disorder with severe rapid cycling and suicidal thoughts. I found out about lithium orotate about 1 month ago. It has been helping. I have been trying to find the right dose. I will try the 30 mg per day. I was a mental health counselor, and I know that the meds caused my awful decline. I thank you for your work.

  6. kquilt@gmail.com' K
    Feb 08, 2015 @ 22:02:35

    Hello Madeline, What is no-Pilate disorder?

  7. peace_moon_stars@yahoo.com' Marie
    Feb 17, 2015 @ 10:36:59

    I’m taking lithium carbonate 300 mg 2x a day and believe it is causing me weight gain. If I switch to lithium orotate, will it help me lose weight and how much should I take?

  8. peace_moon_stars@yahoo.com' Kelly
    May 04, 2015 @ 13:10:13

    Im on 300 mg lithium carbonate also and wondering how much to take. I feel anxious if I wean down to 1x day but I need to stop the weight gain also. I’m thinking of getting the 120 mg lithium orotate. Thanks

  9. carolgotmail@gmail.com' Carol
    May 04, 2015 @ 18:46:45

    Hi Michelle,
    I really like the layout of your article. I’ve been doing a lot of research on the internet and I’ve read just about every article you had referred to. Your article here is extremely comprehensive and easy to understand. You put all the information anyone would need on the subject of lithium orotate.

    My son was diagnosed bipolar 1 with psychosis and attempted suicide twice. Long story short, he’s doing great now and is only taking 900 mg/day of the lithium carbonate. I was researching lithium orotate for my personal severe insomnia and anxiety which has been ongoing for many years. When I found lithium orotate I decided to try it for myself. I’m a holistic nutritionist and wanted to take a natural supplement. I’ve tried everything else. I’ve only been taking it at bedtime for a few days and I need to give it time to see if the dosage needs to be tweaked.

    That said, I was trying yo tell my son,who is 27 yo, to ask his doc about switching. I’m sure he nervous to change anything because of what he’s been through.

    I’m really concerned about the future, almost guaranteed, kidney and thyroid damage. Any suggestions of how to help him understand? I’ve sent Jim articles and my husband doesn’t want me to push the issue.

    Thank you for a very interesting and clear read!

  10. Craigjcarlson@hotmail.com' Craig
    May 15, 2015 @ 20:47:42

    Wonderful artical best one I’ve heard with lithium orotate(LO) I’ve been reading up on LO and how much LO per day would one have to take to reach a toxic level would you say? Thanks you

  11. bobfrostmail@aol.com' Jake
    Aug 12, 2015 @ 11:15:08

    I’ve been under a fair bit of stress lately (work related) and have been using alcohol in evenings to deal with it – a little bit too much of the stuff and a little bit too often. I haven’t regarded this as a problem but I’ve been monitoring the situation closely in the belief that booze can very quickly become a problem. I’ve been addressing the situation with supplements. I feel that 15 mg of elemental lithium orotate twice a day has been helpful. I also think I’ve benefited from a large intake of probiotics. My alcohol intake is down – I don’t feel the need for it – and I see these two products as essential in this regard. Also my mood seems better. (I also take a full range of other vitamins including injectable B12. And I take MSM. I balance Vitamin A with Vitamin D very carefully.)

  12. paolathome@hotmail.com' Ana Thome
    Nov 25, 2015 @ 10:02:54

    Hello, I read the 1979 abstract which says: “…The renal lithium clearance was significantly lower, the kidney weight and the lithium concentrations in serum, kidney and heart significantly higher after injection of lithium orotate than after injection of lithium carbonate…”
    It says that the concentration was higher with orotate than with carbonate
    It doesn´t make sense
    rds
    Ana

  13. jy13@shaw.ca' Julianna
    Nov 28, 2015 @ 21:58:49

    I’ve been on 600 mg lithium carbonate for too long and I took it down to 450 mg of lithium carbonate AND added 5 mg. of lithium orotate….I had massive headaches…for too long. I need some guidance as to how to make this transitions without withdrawals or having an episode.

  14. Miacinque@gmail.com' Mia
    Dec 27, 2015 @ 14:58:25

    I very much need help transitioning from lithium carbonate to lithium orotate. I do not want to do it on my own! My physchiatrist never heard of it but has given me the green light to take any form of lithium as it has stopped my bipolar psychosis but irritates my bowel so. I’ve only been on it for one month.

    Please help. Need direction and advisement in order to make the switch and then spread the word if it helps me!

    Thank you!

  15. Miacinque@gmail.com' Mia
    Dec 27, 2015 @ 21:09:08

    If I take 600mg lithium carbonate, how much lithium orotate would I take for the same affect?

  16. Dr. Michelle Kmiec
    Dec 28, 2015 @ 11:07:33

    200 mg would achieve the same effect

  17. careydubay@gmail.com' Carey
    Jan 27, 2016 @ 15:04:39

    I tried to contact your drmichelle@… but can’t get through.
    I have Bi-polar disorder and have taken Lithium Carbonate for 20 years. I want to switch to Lithium Orotate. I presently take 900mg LC daily. How much LO would replace LC? If you can’t say for liability reasons, would you please explain how to figure it out? My body desperately needs to do this. This knowledge is a gift from God. Thank you so much!

  18. Sebaroussel@yahoo.fr' Sebastien
    May 05, 2016 @ 11:56:46

    I take 1200 mg lithium carbonate, how much lithium orotate i must take? Thank you for your help.

  19. ljmosher1@gmail.com' Linda Mosher
    May 18, 2016 @ 09:59:41

    Anyone who has Parkinson’s or other neurological diseases should read this article about a lithium study done. Link here:

    http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4621308/

    I have had some tremors and also suffer from PTSD but after taking lithium orotate
    the symptoms settled down so the article confirmed my suspicions that lithium was helping. I stopped the lithium of late and the symptoms have started to return. I was only taking 2.5-5 mgs of lithium orotate. This article says they used 1-2 mM but I don’t seem to find what kind they used or how much that really is. Any info you can offer would be helpful. It was recommended that it be used along with Parkinson’s drugs and/or valproic acid, so I need to do more research on where to get that as I am not on any meds for Parkinson’s.

  20. Lithium Alzheimer Treatment Options | Treatment for Alzheimer
    Jun 08, 2016 @ 12:02:31

    […] Natural Treatment for Bipolar Disorder and Alzheimer’s … – Audio By: Dr Michelle Kmiec – Natural Treatment for Bipolar Disorder and Alzheimer’s Ignored! […]

  21. Softballfolks24@yahoo.com' Debbie
    Jun 29, 2016 @ 13:32:12

    I was diagnosed with cyclothymic disorder 4 mos ago and prescribed lithium carbonate 300mg bid. I’m telling u it worked wonders and absolutely changed my life. I love it BUT one major problem…after about 2 months my hair started falling out!!! I bought selenium, biotin, primrose oil supplements but 2 months later since coming out. With the approval of my PCP I cut my lithium dose in half…1 month later it’s still falling out. My PCP doesn’t seem very concerned and believes at some point it will stop. He doesn’t want to change my med. I’m not willing to wait til I’m bald to make a move. I only have 1/3 of the hair I had before. I ordered lithium orotate on-line last nite and I’m hoping I can stay on lithium AND keep my hair!!! What dosage should I start with?

  22. andrewky_hillam@hotmail.com' Andrew
    Jun 30, 2016 @ 04:45:36

    Hi there, i have just started lithium carbonate, this is my first day on it, i really dont want to take it now due to all the side effects, and reading all these comments, The dr has started me on 250mg, how much lithium orotate would i need instead, thanks very much for your help.

  23. Olivia.heady@snhu.edu' Olivia
    Jul 04, 2016 @ 23:52:45

    Hi Can you please let me know if Lithium orotate if taken as prescribed is effective for severe mania with delusions? I cannot find information whether or not it would be effective enough for my case of bipolar. I currently take ziprisadone, 80 mg daily, which is effective however I am not happy with the possibility of the severe side effects that can result from prolonged use of the medication.

  24. Dr. Michelle Kmiec
    Jul 11, 2016 @ 16:55:12

    Hello, based on the formula in the article you would need less than 100 mg lithium orotate per day.

  25. Dr. Michelle Kmiec
    Jul 11, 2016 @ 16:57:56

    Hello, I am not sure how lithium orotate compares to ziprisadone. Perhaps you can ask your doctor what amount of lithium carbonate they may suggest and then we could go from there. Perhaps lithium carbonate was not a good option for you since the dosage may have been too high, and thus a danger to your kidneys. If that is the case, then lithium orotate would be far healthier for you and likely very effective.

  26. Dr. Michelle Kmiec
    Jul 11, 2016 @ 16:58:55

    Hello, to achieve the same effect you would start at 100 mg per day.

  27. Dr. Michelle Kmiec
    Jul 11, 2016 @ 16:59:57

    Hello! To achieve the same effect based on the formula in the article you would need 400 mg lithium orotate per day.

  28. Dr. Michelle Kmiec
    Jul 11, 2016 @ 17:00:59

    Hi! to achieve the same effect based on the formula in the article you would 300 mg lithium orotate per day. 🙂

  29. md.younus.87@gmail.com' Jonah
    Jul 13, 2016 @ 12:59:56

    Hello,

    I have been taking Lithium Carbonate 300 mg (3 tablets for total of 900 mg) for 2 years now. Helped keep my bipolar in check. Had good results until one fine day my tinnitus got worse. I stopped taking it but 2 months and tinnitus symptoms still didnt go away. Visited ENT, he said if tinnitus is due to Lithium – it should have stopped after discontinuing the medicine, he advice me to start again since stopping didnt really help. My hearing tests were normal – no hearing loss. Consulted my psychiatrist again and he also recommended restarting Lithium, I did and after a couple of days tinnitus got worse!!! I stopped again this time deciding that I will not start again regardless what the doctors say!!!

    Now i came across this Lithium Orotate and considering to take it to manage my Bipolar condition. Any recommendations would be welcome, what dosage should I start with?

    FYI – my lab result for my for Lithium, Serum is <0.1. Normal range should be 0.6-1.4

  30. themrne4life@ymail.com' LJ
    Jul 13, 2016 @ 23:24:44

    When you tell someone too take 300mg a day do you just mean the total mg of the Orotate pill taken or ensure that they are taking 300mg of Lithium?

  31. Dr. Michelle Kmiec
    Jul 14, 2016 @ 06:28:34

    Hello, if you read the article especially the area where it states the formula of equivalence between lithium carbonate and orotate, the key thing is to also look at the elemental. 300 mg of lithium carbonate is not the same as lithium oroate. The same achieve effect however occurs with 100 mg of lithium oroate. When I suggest to someone the amount to take, I am referring to the formula that is stated within the article.

  32. angelab45@optus.com.au' Mary
    Jul 20, 2016 @ 18:19:59

    I just learned that Lithium Orotate is banned in Australia. I have ordered 5 mg tablets from USA a few times without any trouble so it must have been a fluke that they got through customs. I don’t know what to do now as I want to keep taking it. I don’t have any serious health problems I just like to take it as a preventive measure against alzhiemers.

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